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A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5'-3' messenger RNA decay.

Chang CT, Muthukumar S, Weber R, Levdansky Y, Chen Y, Bhandari D, Igreja C, Wohlbold L, Valkov E, Izaurralde E
Nucleic Acids Res. 2019 Sep 26;47(17):9282-9295. doi: 10.1093/nar/gkz633. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
148901pETM-41P-HsXRN1_1174-1649-Strep_AHBacterial Expression of HsXRN1_1174-1649
148902pT7-EGFP-C1-HsNot8-D40AE42A_AHMammalian Expression of HsNot8-D40AE42A
148903pT7-EGFP-C1-HsXRN1_1174-1649_AHMammalian Expression of HsXRN1_1174-1649
148904pT7-EGFP-C1-HsXRN1-del1174-1649_AHMammalian Expression of HsXRN1-del1174-1649

Antibodies from Article