The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2.
Loh B, Jonas S, Izaurralde E
Genes Dev. 2013 Oct 1;27(19):2125-38. doi: 10.1101/gad.226951.113.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 147552 | pcDNA3.1-MS2-HA-HsSmg5_T | Mammalian Expression of HsSmg5 |
| 147553 | pcDNA3.1-MS2-HA-HsSmg5-del133-155_T | Mammalian Expression of HsSmg5-del133-155 |
| 147554 | pcDNA3.1-MS2-HA-HsSmg5-del133-155-G120E_T | Mammalian Expression of HsSmg5-del133-155-G120E |
| 147555 | pcDNA3.1-MS2-HA-HsSmg5-Q123E_T | Mammalian Expression of HsSmg5-Q123E |
| 147556 | pcDNA3.1-MS2-HA-HsSmg7_T | Mammalian Expression of HsSmg7 |
| 147557 | pcDNA3.1-MS2-HA-HsSmg7_1-633_T | Mammalian Expression of HsSmg7_1-633 |
| 147558 | pcDNA3.1-MS2-HA-HsSmg7_633-1091_T | Mammalian Expression of HsSmg7_633-1091 |
| 147643 | pCIneo-lambdaN-HA-HsDCP2-E148Q_U | Mammalian Expression of HsDCP2-E148Q |
| 147644 | pCIneo-lambdaN-HA-HsSmg7_1-633_U | Mammalian Expression of HsSmg7_1-633 |
| 147645 | pCIneo-lambdaN-HA-HsSmg7_1-633-shRNAres_U | Mammalian Expression of HsSmg7_1-633-shRNAres |
| 147646 | pCIneo-lambdaN-HA-HsSmg7_633-1091-siRNAres_U | Mammalian Expression of HsSmg7_633-1091-siRNAres |
| 147647 | pLNHA-C1-HsNot8-D40AE42A_U | Mammalian Expression of HsNot8-D40AE42A |
| 147648 | pnEA-NvG-HsNot8_1-240_U | Bacterial Expression of HsNot8_1-240 |
| 147649 | pnEA-NvG-HsNot8_13-240_U | Bacterial Expression of HsNot8_13-240 |
| 147650 | pT7-EGFP-C1-HsDCP2-E148Q_U | Mammalian Expression of HsDCP2-E148Q |
| 147760 | pCIneo-lambdaN-HA-HsPNRC2_V | Mammalian Expression of HsPNRC2 |
| 147761 | pCIneo-V5-SBP-MBP-HsPNRC2_V | Mammalian Expression of HsPNRC2 |
| 147762 | pN1-HsSmg5_267-1017-V5-SBP-MBP_V | Mammalian Expression of HsSmg5_267-1017 |
| 147763 | pN1-HsSmg5-del133-155-V5-SBP-MBP_V | Mammalian Expression of HsSmg5-del133-155 |
| 147764 | pN1-HsSmg5-del267-809-V5-SBP-MBP_V | Mammalian Expression of HsSmg5-del267-809 |
| 147765 | pN1-HsSmg5-del810-846-V5-SBP-MBP_V | Mammalian Expression of HsSmg5-del810-846 |
| 147766 | pN1-HsSmg5-del847-1017-V5-SBP-MBP_V | Mammalian Expression of HsSmg5-del847-1017 |
| 147767 | pN1-HsSmg5-G120E-del133-155-V5-SBP-MBP_V | Mammalian Expression of HsSmg5-G120E-del133-155 |
| 147768 | pN1-HsSmg5-V5-SBP-MBP_V | Mammalian Expression of HsSmg5 |
| 147769 | pnYC-NpM-HsSMG7opt_732-1091_V | Bacterial Expression of HsSMG7opt_732-1091 |
| 147819 | pcDNA3.1-MS2-HA-HsSmg5-G120E_W | Mammalian Expression of HsSmg5-G120E |