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Expanding the genome-targeting scope and the site selectivity of high-precision base editors.

Tan J, Zhang F, Karcher D, Bock R
Nat Commun. 2020 Jan 31;11(1):629. doi: 10.1038/s41467-020-14465-z. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
141318pJT112_GalL_nCDA1-xBE3Expressing base editor nCDA1-xBE3 in yeast cells
145079pJT113_GalL_cCDA1-xBE3Expressing base editor cCDA1-xBE3 in yeast cells
145086pJT121_GalL_nCDA1-VQRBE3Expressing base editor nCDA1-VQRBE3 in yeast cells
145087pJT122_GalL_cCDA1-VQRBE3Expressing base editor cCDA1-VQRBE3 in yeast cells
145094pJT130_GalL_nCDA1-NGBE3Expressing base editor nCDA1-NGBE3 in yeast cells
145095pJT131_GalL_cCDA1-NGBE3Expressing base editor cCDA1-NGBE3 in yeast cells
145102pJT139_GalL_nCDA1-VRERBE3Expressing base editor nCDA1-VRERBE3 in yeast cells
145103pJT140_GalL_cCDA1-VRERBE3Expressing base editor cCDA1-VRERBE3 in yeast cells
145116pJT166_GalL_A3A-BE3Expressing base editor A3A-BE3 in yeast cells
145119pJT169_GalL_A3AΔ186-BE3Expressing base editor A3AΔ186-BE3 in yeast cells
145120pJT170_GalL_A3AΔ182-BE3Expressing base editor A3AΔ182-BE3 in yeast cells
145121pJT171_GalL_A3AΔ178-BE3Expressing base editor A3AΔ178-BE3 in yeast cells
145122pJT173_GalL_A3A-R128A-BE3Expressing base editor A3A-R128A-BE3 in yeast cells
145123pJT174_GalL_A3A-Y130F-BE3Expressing base editor A3A-Y130F-BE3 in yeast cells
145124pJT175_GalL_A3A(Y130F)Δ186-BE3Expressing base editor A3A(Y130F)Δ186-BE3 in yeast cells
145125pJT176_GalL_eA3A-BE3Expressing base editor eA3A-BE3 in yeast cells

Antibodies from Article