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Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway.

Guo X, Aviles G, Liu Y, Tian R, Unger BA, Lin YT, Wiita AP, Xu K, Correia MA, Kampmann M
Nature. 2020 Mar;579(7799):427-432. doi: 10.1038/s41586-020-2078-2. Epub 2020 Mar 4. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
141281pXG237ATF4 translational reporter
141282pXG260CMV:EGFP (as control for pXG237)
141283pXG289OE of DELE1
141284pXG290OE of HRI

Antibodies from Article