Optogenetic control of cofilin and alphaTAT in living cells using Z-lock.

Stone OJ, Pankow N, Liu B, Sharma VP, Eddy RJ, Wang H, Putz AT, Teets FD, Kuhlman B, Condeelis JS, Hahn KM
Nat Chem Biol. 2019 Dec;15(12):1183-1190. doi: 10.1038/s41589-019-0405-4. Epub 2019 Nov 18. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

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ID	Plasmid	Purpose
175290	Z-lock αTAT	light-controlled analog of the alpha-tubulin acetylase αTAT
141137	Z-lock cofilin	controlling the actin-severing ability of cofilin with light
141136	Mammalian expression: Z-lock cofilin dark state mutant	a control for optogenetic cofilin analog
141135	E. coli expression: Z-lock cofilin dark state mutant	a control for optogenetic cofilin analog