Optogenetic control of cofilin and alphaTAT in living cells using Z-lock.
Stone OJ, Pankow N, Liu B, Sharma VP, Eddy RJ, Wang H, Putz AT, Teets FD, Kuhlman B, Condeelis JS, Hahn KM
Nat Chem Biol. 2019 Dec;15(12):1183-1190. doi: 10.1038/s41589-019-0405-4. Epub 2019 Nov 18.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 141135 | E. coli expression: Z-lock cofilin dark state mutant | a control for optogenetic cofilin analog |
| 141136 | Mammalian expression: Z-lock cofilin dark state mutant | a control for optogenetic cofilin analog |
| 141137 | Z-lock cofilin | controlling the actin-severing ability of cofilin with light |
| 175290 | Z-lock αTAT | light-controlled analog of the alpha-tubulin acetylase αTAT |