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Nuclear Excluded Autism-Associated Phosphatase and Tensin Homolog Mutations Dysregulate Neuronal Growth.

Fricano-Kugler CJ, Getz SA, Williams MR, Zurawel AA, DeSpenza T Jr, Frazel PW, Li M, O'Malley AJ, Moen EL, Luikart BW
Biol Psychiatry. 2018 Aug 15;84(4):265-277. doi: 10.1016/j.biopsych.2017.11.025. Epub 2017 Dec 2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
140732FUG-PtenLentiviral vector to overexpress wild-type human PTEN as a GFP-PTEN fusion protein
140733FUG-PtenH93RLentiviral vector to overexpress the autism-associated PTEN mutation H93R as a GFP-PTEN fusion protein
140735FUG-PtenD252GLentiviral vector to overexpress the autism-associated PTEN mutation D252G as a GFP-PTEN fusion protein
140736FUG-PtenW274LLentiviral vector to overexpress the autism-associated PTEN mutation W274L as a GFP-PTEN fusion protein
140737FUG-PtenN276SLentiviral vector to overexpress the PTEN mutation N276S as a GFP-PTEN fusion protein
140738FUG-T2A-PtenLentiviral vector to overexpress human PTEN and GFP
140739FUG-T2A-H93RLentiviral vector to overexpress the autism-associated PTEN mutation H93R and GFP as two separate proteins
140740FUG-T2A-F241SLentiviral vector to overexpress the autism-associated PTEN mutation F241S and GFP as two separate proteins
140741FUG-T2A-D252GLentiviral vector to overexpress the autism-associated PTEN mutation D252G and GFP as two separate proteins
140742FUG-T2A-W274LLentiviral vector to overexpress the autism-associated PTEN mutation W274L and GFP as two separate proteins

Antibodies from Article