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Experimental evidence for the age dependence of tau protein spread in the brain.

Wegmann S, Bennett RE, Delorme L, Robbins AB, Hu M, McKenzie D, Kirk MJ, Schiantarelli J, Tunio N, Amaral AC, Fan Z, Nicholls S, Hudry E, Hyman BT
Sci Adv. 2019 Jun 26;5(6):eaaw6404. doi: 10.1126/sciadv.aaw6404. eCollection 2019 Jun. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
140424AAV.CBA.eGFP.2A.wtTauAAV.CBA.eGFP.2A.wtTau propagation reporter WT-2N4R-hTau
140425AAV.CBA.eGFP.2A.P301L-TauAAV.CBA.eGFP.2A.P301L-Tau propagation reporter P301L-2N4R-hTau

Antibodies from Article