Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice.
Shen M, Wang F, Li M, Sah N, Stockton ME, Tidei JJ, Gao Y, Korabelnikov T, Kannan S, Vevea JD, Chapman ER, Bhattacharyya A, van Praag H, Zhao X
Nat Neurosci. 2019 Mar;22(3):386-400. doi: 10.1038/s41593-019-0338-y. Epub 2019 Feb 11.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 157859 | 61426-hU6-shmFmr1-EF1a-mCherry | Expresses a shRNA targeting mouse Fmr1 gene |
| 157860 | 61427-sgHtt_6 | Expresses a sgRNA targeting mouse Htt promoter for gene activation using the SAM system |
| 157861 | 61427-sgHtt_10 | Expresses a sgRNA targeting mouse Htt promoter for gene activation using the SAM system |