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Regulation of the RNAPII Pool Is Integral to the DNA Damage Response.

Tufegdzic Vidakovic A, Mitter R, Kelly GP, Neumann M, Harreman M, Rodriguez-Martinez M, Herlihy A, Weems JC, Boeing S, Encheva V, Gaul L, Milligan L, Tollervey D, Conaway RC, Conaway JW, Snijders AP, Stewart A, Svejstrup JQ
Cell. 2020 Mar 5. pii: S0092-8674(20)30153-7. doi: 10.1016/j.cell.2020.02.009. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
139404pFRT-TO-RPB1-His WT CRres si2,4RDox-inducible, wt C-terminal His tagged RPB1, resistant to siRNAs 2 & 4, for generation of TRex flp In cells.
139405pFRT-TO-RPB1-His K1268R CRres si2,4RDox-inducible, K1268R C-terminal His tagged RPB1, resistant to siRNAs 2 & 4, for generation of TRex flp In cells.
139406pFRT-TO-RPB1-His K1278R CRres si2,4RDox-inducible, K1278R C-terminal His tagged RPB1, resistant to siRNAs 2 & 4, for generation of TRex flp In cells.
139407pFRT-TO-RPB1-His K710,719R CRres si2,4RDox-inducible, K710, 719R C-terminal His tagged RPB1, resistant to siRNAs 2 & 4, for generation of TRex flp In cells.
139408pFRT-TO-RPB1-His K751,758,767R CRres si2,4RDox-inducible, K751, 758, 767R C-terminal His tagged RPB1, resistant to siRNAs 2 & 4, for generation of TRex flp In cells.
139409pFRT-TO-RPB1-His CRres K619,627,642R si2,4RDox-inducible, K619, 627, 642R C-terminal His tagged RPB1, resistant to siRNAs 2 & 4, for generation of TRex flp In cells.

Antibodies from Article