Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.
Velazquez L, Mogensen KE, Barbieri G, Fellous M, Uze G, Pellegrini S
J Biol Chem. 1995 Feb 17;270(7):3327-34. doi: 10.1074/jbc.270.7.3327.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 139352 | pRC/CMV-TYK2(delta)KL-VSV | Expression of TYK2 protein missing the kinase-like (pseudokinase) domain |
| 139353 | pRC/CMV-TYK2(delta)TK-VSV | Expression of TYK2 protein missing the tyrosine kinase (TK) domain (aa 1-895) |