An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin.
Ng TL, Rohac R, Mitchell AJ, Boal AK, Balskus EP
Nature. 2019 Feb;566(7742):94-99. doi: 10.1038/s41586-019-0894-z. Epub 2019 Feb 6.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 139282 | pET28a-SznE | expresses SznE in E. coli |
| 139564 | pET28a-SznF | expresses SznF in E. coli |
| 139565 | pET28a-SznF E215A | expresses SznF E215A in E. coli |
| 139566 | pET28a-SznF H407A H409A H448A | expressed SznF H407A H409A H448A in E. coli |
| 139590 | pET28a SznF H225A | expresses SznF H225A |
| 139591 | pET28a SznF E281A | expresses SznF E281A |
| 139592 | pET28a D315A | expresses SznF D315A |