Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration.
Ryan VH, Perdikari TM, Naik MT, Saueressig CF, Lins J, Dignon GL, Mittal J, Hart AC, Fawzi NL
EMBO J. 2021 Feb 1;40(3):e105001. doi: 10.15252/embj.2020105001. Epub 2020 Dec 22.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 139112 | TOG_D1 | express first domain (1-250) of TOG |
| 139113 | hnRNPF_PLD | express prion like domain of hnRNPF |
| 139114 | pTHMT_hnRNPF_FL | express FL hnRNPF with N-terminal maltose binding protein tag |
| 139115 | pTHMT_hnRNPF_deltaPLD | express FL hnRNPF without the prion like domain with N-terminal maltose binding protein tag |
| 139116 | HRP-1LC | express the LC of HRP-1 |
| 139117 | pJ4M_HRP-1_FL | express HRP-1 with a C-terminal maltose binding protein tag |
| 139118 | hnRNPA2_LC_nocharge | express hnRNPA2 LC with no charged residues |
| 139119 | hnRNPA2_LC_nocharge_wR | express hnRNPA2 LC with no charged residues with R added back |
| 139120 | hnRNPA2_LC_RtoK | express hnRNPA2 LC where all R are K |
| 139121 | hnRNPA2_LC_NtoS | express hnRNPA2 with all N changed to S |
| 139122 | hnRNPA2_LC_5E | express hnRNPA2 with 5 serine changed to glutamate |
| 139123 | hnRNPA2_LC_12E | express hnRNPA2 with all serine change to glutamate |
| 139124 | hnRNPF_PLD_YtoS | express hnRNPF PLD with all Y changed to S |
| 139125 | hnRNPF_PLD_StoA | express hnRNPF PLD with all S changed to A |
| 139126 | FUS_LC_charge | express FUS LC with an hnRNPA2 LC-like charge patterning |
| 139127 | FUS_LC_charge_RtoK | express FUS LC with hnRNPA2-like charge patterning where all R are changed to K |
| 139128 | FUS_LC_withR | express FUS LC with the same number and spacing of arginines as hnRNPA2 LC |