Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity.
Yu Y, Leete TC, Born DA, Young L, Barrera LA, Lee SJ, Rees HA, Ciaramella G, Gaudelli NM
Nat Commun. 2020 Apr 28;11(1):2052. doi: 10.1038/s41467-020-15887-5.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 138338 | pCMV-BE4-PpAPOBEC1 H122A | Mammalian expression plasmid for BE4-PpABOBEC1H122A |
| 138340 | pCMV-BE4-RrA3F | Mammalian expression plasmid for BE4-RrA3F |
| 138341 | pCMV-BE4-RrA3F F130L | Mammalian expression plasmid for BE4-RrA3F F130L |
| 138342 | pCMV-BE4-AmAPOBEC1 | Mammalian expression plasmid for BE4-AmABOBEC1 |
| 138343 | pCMV-BE4-SsAPOBEC3B | Mammalian expression plasmid for BE4-SsAPOBEC3B |
| 138344 | pCMV-BE4-SsAPOBEC3B R54Q | Mammalian expression plasmid for BE4-SsAPOBEC3B R54Q |
| 138345 | pCMV-BE4-PpAPOBEC1 R33A | Mammalian expression plasmid for BE4-PpABOBEC1 R33A |
| 138349 | pCMV-BE4-PpAPOBEC1 | Mammalian expression plasmid for BE4-PpABOBEC1 |