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AKAP95 Organizes a Nuclear Microdomain to Control Local cAMP for Regulating Nuclear PKA.

Clister T, Greenwald EC, Baillie GS, Zhang J
Cell Chem Biol. 2019 Jun 20;26(6):885-891.e4. doi: 10.1016/j.chembiol.2019.03.003. Epub 2019 Apr 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
138254pcDNA3.1(+)-AKAP95-FRBFull-length AKAP95 fused to FRB (rapamycin-binding domain). Used in conjunction with pcDNA3-FKBP-ICUE3-NLS to monitor cAMP dynamics within AKAP95 nanodomain.
138255pcDNA3-FKBP-ICUE3-NLSFRET-based cAMP indicator fused to FKBP (rapamycin-binding domain); nuclear targeted. Used in conjuction with pcDNA3.1(+)-AKAP95-FRB to monitor cAMP dynamics within AKAP95 nanodomain.

Antibodies from Article