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Augmentation of Bri2 molecular chaperone activity against amyloid-beta reduces neurotoxicity in mouse hippocampus in vitro.

Chen G, Andrade-Talavera Y, Tambaro S, Leppert A, Nilsson HE, Zhong X, Landreh M, Nilsson P, Hebert H, Biverstal H, Fisahn A, Abelein A, Johansson J
Commun Biol. 2020 Jan 20;3(1):32. doi: 10.1038/s42003-020-0757-z. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
138134pT7NT*-Bri2 113-231 R221EExpresseds human Bri2 BRICHOS R221E mutant in E. coli

Antibodies from Article