Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses.
Levy JM, Yeh WH, Pendse N, Davis JR, Hennessey E, Butcher R, Koblan LW, Comander J, Liu Q, Liu DR
Nat Biomed Eng. 2020 Jan;4(1):97-110. doi: 10.1038/s41551-019-0501-5. Epub 2020 Jan 14.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 137171 | CMV_Npu-BE3.9max N-terminal | Expresses the N-terminal split-intein fragment of BE3.9max from the CMV promoter |
| 137172 | CMV_Npu-BE3.9max C-terminal | Expresses the C-terminal split-intein fragment of BE3.9max from the CMV promoter |
| 137173 | CMV_Npu-ABEmax N-terminal | Expresses the N-terminal split-intein fragment of ABEmax from the CMV promoter |
| 137174 | CMV_Npu-ABEmax C-terminal | Expresses the C-terminal split-intein fragment of ABEmax from the CMV promoter |
| 137175 | Cbh_v5 AAV-CBE N-terminal | AAV genome: expresses the N-terminal of v5 AAV-CBE from the Cbh promoter, and U6-sgRNA |
| 137176 | Cbh_v5 AAV-CBE C-terminal | AAV genome: expresses the C-terminal of v5 AAV-CBE from the Cbh promoter, and U6-sgRNA |
| 137177 | Cbh_v5 AAV-ABE N-terminal | AAV genome: expresses the N-terminal of v5 AAV-ABE from the Cbh promoter |
| 137178 | Cbh_v5 AAV-ABE C-terminal | AAV genome: expresses the C-terminal of v5 AAV-ABE from the Cbh promoter, and U6-sgRNA |
| 137179 | CMV_Npu-saBE3.9max N-terminal | Expresses the N-terminal split-intein fragment of S. aureus BE3.9max from the CMV promoter |
| 137180 | CMV_Npu-saBE3.9max C-terminal | Expresses the C-terminal split-intein fragment of S. aureus BE3.9max from the CMV promoter |
| 137181 | CMV_Npu-saBE3.9max_KKH C-terminal | Expresses the C-terminal split-intein fragment of S. aureus BE3.9max (KKH variant) from the CMV promoter |
| 137182 | Cbh_v5 AAV-saCBE N-terminal | AAV genome: expresses the N-terminal of S. aureus v5 AAV-CBE from the Cbh promoter, U6-sgRNA |
| 137183 | Cbh_v5 AAV-saCBE C-terminal | AAV genome: expresses the C-terminal of S. aureus v5 AAV-CBE from the Cbh promoter, and U6-sgRNA |
| 137184 | Cbh_v5 AAV-saCBE_KKH C-terminal | AAV genome: expresses the C-terminal of S. aureus v5 AAV-CBE, and U6-sgRNA (KKH variant). |