Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.
Shen K, Valenstein ML, Gu X, Sabatini DM
J Biol Chem. 2019 Feb 22;294(8):2970-2975. doi: 10.1074/jbc.AC119.007382. Epub 2019 Jan 16.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 136146 | [pSK600] pRK5 HA-Nprl2(R78A) | mammalian expression of Nprl2 |