Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons.
Ahfeldt T, Ordureau A, Bell C, Sarrafha L, Sun C, Piccinotti S, Grass T, Parfitt GM, Paulo JA, Yanagawa F, Uozumi T, Kiyota Y, Harper JW, Rubin LL
Stem Cell Reports. 2019 Dec 20. pii: S2213-6711(19)30444-8. doi: 10.1016/j.stemcr.2019.12.005.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 135814 | pTAHR TH-p2a-TD:Tomato (floxed selection Puro) | Fluorescent reporter for knock-in of TdTomato into the TH locus |
| 135815 | pTACR TH1-p2aGFP | CRISPR based on px330 p2aGFP targeting TH gene near stop codon |
| 135816 | pTACR TH2-p2aGFP | CRISPR based on px330 p2aGFP targeting TH gene near stop codon |