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Expanding C-T base editing toolkit with diversified cytidine deaminases.

Cheng TL, Li S, Yuan B, Wang X, Zhou W, Qiu Z
Nat Commun. 2019 Aug 9;10(1):3612. doi: 10.1038/s41467-019-11562-6. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
135019N-4-BEC-T base editing using LjCDA1L1_4 fused to N terminal of nCas9
135023N-8-BEC-T base editing using LpCDA1L1_1 fused to N terminal of nCas9
135029C-1-BEC-T base editing using PmCDA1L1_4 fused to C terminal of nCas9
135034C-6-BEC-T base editing using LjDA1L2_2 fused to C terminal of nCas9
135035C-7-BEC-T base editing using LpCDA1L1_1 fused to C terminal of nCas9
135039C-11-BEC-T base editing using LpCDA1L2_2 fused to C terminal of nCas9
135040C-12-BEC-T base editing using LjCDA1L2_1 fused to C terminal of nCas9
135041C-13-BEC-T base editing using LpCDA1L1_4 fused to C terminal of nCas9

Antibodies from Article