HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice.
Luo H, Zhu G, Xu J, Lai Q, Yan B, Guo Y, Fung TK, Zeisig BB, Cui Y, Zha J, Cogle C, Wang F, Xu B, Yang FC, Li W, So CWE, Qiu Y, Xu M, Huang S
Cancer Cell. 2019 Dec 9;36(6):645-659.e8. doi: 10.1016/j.ccell.2019.10.011. Epub 2019 Nov 27.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
134989 | pLKO5-SgHottip-GFP-CRISPRi | dCas9-mediated inactivation of HOTTIP in mammalian cells |
134990 | pLKO5-SgHottip-GFP-CRISPRa | dCas9-mediated activation of HOTTIP in mammalian cells |