The DEAD-box protein DDX43 (HAGE) is a dual RNA-DNA helicase and has a K-homology domain required for full nucleic acid unwinding activity.
Talwar T, Vidhyasagar V, Qing J, Guo M, Kariem A, Lu Y, Singh RS, Lukong KE, Wu Y
J Biol Chem. 2017 Jun 23;292(25):10429-10443. doi: 10.1074/jbc.M117.774950. Epub 2017 May 3.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 134574 | pET28a-DDX43 | Express human DDX43 protein (WT, full-length) in E. coli |
| 134575 | pET28a-DDX43-K292A | Express human DDX43 mutant (K292A, ATPase dead) in E. coli |
| 134577 | pET28a-DDX43-FL-G84D | Express human DDX43 mutant (full-length with G84D mutation) in E. coli |
| 134588 | pET28a-DDX43-NT-G46D | Express human DDX43 N-terminal region (1-253 aa, with G46D mutation) in E. coli |