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Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III.

Chang CL, Weigel AV, Ioannou MS, Pasolli HA, Xu CS, Peale DR, Shtengel G, Freeman M, Hess HF, Blackstone C, Lippincott-Schwartz J
J Cell Biol. 2019 Aug 5;218(8):2583-2599. doi: 10.1083/jcb.201902061. Epub 2019 Jun 21. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
134461mApple-M1 SpastinM1 Spastin expression
134462mApple-M1 SpastinHFDDM1 SpastinHFDD expression
134463mApple-M1 SpastinK388RM1 SpastinK388R expression
134464mApple-M1 SpastinE442QM1 SpastinE442Q expression
134465mEmerald-M11-92M11-92 expression
134466mApple-M11-92M11-92 expression
134467DsRed2-M11-92M11-92 expression
134468mEmerald-GPAT4152-208GPAT4152-208 expression

Antibodies from Article