The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.
Stewart GS, Panier S, Townsend K, Al-Hakim AK, Kolas NK, Miller ES, Nakada S, Ylanko J, Olivarius S, Mendez M, Oldreive C, Wildenhain J, Tagliaferro A, Pelletier L, Taubenheim N, Durandy A, Byrd PJ, Stankovic T, Taylor AM, Durocher D
Cell. 2009 Feb 6;136(3):420-34. doi: 10.1016/j.cell.2008.12.042.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 133976 | pcDNA3-Flag-RNF168 | mammalian expression vector of Flag tagged wild type RNF168 |
| 133977 | pcDNA3-eGFP-NLS-RNF168 | mammalian expression vector of eGFP tagged wild type RNF168 |
| 133978 | pcDNA3-Flag-RNF168 delta MIU1 | mammalian expression vector of Flag tagged RNF168 where the first motif interacting with ubiquitin (MIU) has been deleted |
| 133979 | pcDNA3-Flag-RNF168 delta MIU2 | mammalian expression vector of Flag tagged RNF168 where the second motif interacting with ubiquitin (MIU) has been deleted |
| 133980 | pcDNA5-eGFP-FRT-T0-RNF168 delta MIU1/MIU2 | inducible mammalian expression vector of eGFP tagged RNF168 where both motifs interacting with ubiquitin have been deleted |
| 133981 | pcDNA3-Flag-RNF168 delta MIU1/MIU2 | mammalian expression vector of Flag tagged RNF168 where both motifs interacting with ubiquitin have been deleted |
| 133982 | pcDNA3-Flag-RNF168 delta RING | mammalian expression vector of Flag tagged RNF168 where the N-terminus of RNF168 has been deleted (including RING domain) |
| 133983 | pcDNA3-eGFP-NLS-RNF168 delta RING | mammalian expression vector of eGFP tagged RNF168 where the N-terminus of RNF168 has been deleted (including RING domain) |