Weak membrane interactions allow Rheb to activate mTORC1 signaling without major lysosome enrichment.
Angarola B, Ferguson SM
Mol Biol Cell. 2019 Oct 15;30(22):2750-2760. doi: 10.1091/mbc.E19-03-0146. Epub 2019 Sep 18.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 133766 | pEGFP-C1-RhebL1 | Expresses GFP-tagged RhebL1 in mammalian cells |
| 133767 | pEGFP-C1-Rheb | Expresses GFP-tagged Rheb in mammalian cells |
| 133768 | px459-Rheb sgRNA | Expresses Cas9 and human Rheb sgRNA |
| 133769 | px459-RhebL1 sgRNA | Expresses Cas9 and human RhebL1 sgRNA |