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Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis.

Roczniak-Ferguson A, Ferguson SM
Life Sci Alliance. 2019 Sep 16;2(5). pii: 2/5/e201900358. doi: 10.26508/lsa.201900358. Print 2019 Oct. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
133753pLVX-Puro-TDP-43-WTWild type human TDP-43 in pLVX-Puro lentiviral vector
133754pLVX-Puro-TDP-43-A90VLentiviral expression of human TDP-43 A90V disease mutant in mammalian cells.
133755pLVX-Puro-TDP-43-A315TLentiviral expression of human TDP-43 A315T disease mutant in mammalian cells.
133756pLVX-Puro-TDP-43-A382TLentiviral expression of human TDP-43 A382T disease mutant in mammalian cells.
133757pLVX-Puro-TDP-43-D169GLentiviral expression of human TDP-43 D169G disease mutant in mammalian cells.
133758pLVX-Puro-TDP-43-K263ELentiviral expression of human TDP-43 K263E disease mutant in mammalian cells.
133759pLVX-Puro-TDP-43-M337VLentiviral expression of human TDP-43 M337V disease mutant in mammalian cells.
133760pLVX-Puro-TDP-43-P112HLentiviral expression of human TDP-43 P112H disease mutant in mammalian cells.
133761pLVX-Puro-TDP-43-Q331KLentiviral expression of human TDP-43 Q331K disease mutant in mammalian cells.
133762px459-TDP-43 sgRNA1Expresses Cas9 and human TDP-43 sgRNA
133763px459-TDP 43 sgRNA2Expresses Cas9 and human TDP-43 sgRNA

Antibodies from Article