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Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.

Santasusagna S, Zhu S, Jawalagatti V, Carceles-Cordon M, Ertel A, Garcia-Longarte S, Song WM, Fujiwara N, Li P, Mendizabal I, Petrylak DP, Kelly WK, Reddy EP, Wang L, Schiewer MJ, Lujambio A, Karnes J, Knudsen KE, Cordon-Cardo C, Dong H, Huang H, Carracedo A, Hoshida Y, Rodriguez-Bravo V, Domingo-Domenech J
Cancer Discov. 2023 Sep 7. doi: 10.1158/2159-8290.CD-23-0306. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
133308pGL4-eIF3BExpression of luciferase driven by eIF3B promoter region
133309pGL4-eIF3B MBE2 mutantExpression of luciferase driven by eIF3B promoter region mutated at the E-box binding motif 2
133310pGL4-eIF3B MBE3 mutantExpression of luciferase driven by eIF3B promoter region mutated at the E-box binding motif 3

Antibodies from Article