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Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.

Cheng Z, Biechele T, Wei Z, Morrone S, Moon RT, Wang L, Xu W
Nat Struct Mol Biol. 2011 Oct 9;18(11):1204-10. doi: 10.1038/nsmb.2139. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
132626pET-32M human DKK1c (183–266)expresses human DKK1c (183–266) in E. coli
132627pAcGP67A human LRP6 E1E2 (20–629)expresses human LRP6 E1E2 (20–629) in Hi5 insect cell
132628pAcGP67A human LRP6 E3E4 (630–1244)expresses human LRP6 E3E4 (630–1244) in Hi5 insect cell
132629pAcGP67A human LRP6 E1E4 (20–1244)expresses human LRP6 E1E4 (20–1244) in Hi5 insect cell

Antibodies from Article