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Allosteric activation of the RNF146 ubiquitin ligase by a poly(ADP-ribosyl)ation signal.

DaRosa PA, Wang Z, Jiang X, Pruneda JN, Cong F, Klevit RE, Xu W
Nature. 2015 Jan 8;517(7533):223-6. doi: 10.1038/nature13826. Epub 2014 Oct 19. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
132610pGEX6P-2-human RNF146 full lengthexpresses human RNF146 full length in E. coli
132611pGEX4T-1-human RNF146 RING-WWE (30-183)expresses human RNF146 RING-WWE (30-183) in E. coli

Antibodies from Article