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Extracellular NAD(+) enhances PARP-dependent DNA repair capacity independently of CD73 activity.

Wilk A, Hayat F, Cunningham R, Li J, Garavaglia S, Zamani L, Ferraris DM, Sykora P, Andrews J, Clark J, Davis A, Chaloin L, Rizzi M, Migaud M, Sobol RW
Sci Rep. 2020 Jan 20;10(1):651. doi: 10.1038/s41598-020-57506-9. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
132588pLentiGuide-Puro/CD73-gRNA4Lentiviral gRNA vector targeting human CD73
176532pLV-CMV-hXRCC1-mCherry-HygromCherry fused to the C-terminus of XRCC1 & a hygromycin resistance cassette

Antibodies from Article