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Changes in the allosteric site of human liver pyruvate kinase upon activator binding include the breakage of an intersubunit cation-pi bond.

McFarlane JS, Ronnebaum TA, Meneely KM, Chilton A, Fenton AW, Lamb AL
Acta Crystallogr F Struct Biol Commun. 2019 Jun 1;75(Pt 6):461-469. doi: 10.1107/S2053230X19007209. Epub 2019 Jun 10. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
187975pET15TV-L-hlPYK WTExpresses the human liver pyruvate kinase

Antibodies from Article