Skip to main content
Addgene

CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling.

Mou H, Ozata DM, Smith JL, Sheel A, Kwan SY, Hough S, Kucukural A, Kennedy Z, Cao Y, Xue W
Genome Med. 2019 Apr 16;11(1):21. doi: 10.1186/s13073-019-0627-9. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
138176H513 px330.sgActin.UTR.2CRISPR SONIC: Encodes codon-optimized SpCas9 and gRNA for targeting 3' UTR of β-actin.
138177H517 SONIC HRASV12 donorCRISPR SONIC: HRAS G12V donor plasmid
138178H516 SONIC KrasG12D-IRES-luciferase donorCRISPR SONIC: Kras G12D luciferase donor plasmid.

Antibodies from Article