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Age-dependent accumulation of oligomeric SNCA/alpha-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA).

Ho PW, Leung CT, Liu H, Pang SY, Lam CS, Xian J, Li L, Kung MH, Ramsden DB, Ho SL
Autophagy. 2019 Apr 14:1-24. doi: 10.1080/15548627.2019.1603545. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
102361pcDNA3.1-hSNCA-NEOverexpression of synuclein alpha in mammalian cells
102364pSIN-PAmCherry-mSNCA-NELentiviral overexpression of PA-mCherry synuclein alpha fusion
102365pSIN-PAmCherry-KFERQ-NELentiviral overexpression of PA-mCherry-KFERQ fusion
102366pSIN-hSNCA-NELentiviral overexpression of synuclein alpha

Antibodies from Article