Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation.
Chen TJ, Wang HJ, Liu JS, Cheng HH, Hsu SC, Wu MC, Lu CH, Wu YF, Wu JW, Liu YY, Kung HJ, Wang WC
Commun Biol. 2019 Mar 15;2:105. doi: 10.1038/s42003-019-0343-4. eCollection 2019.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
122690 | pET28a-PKM2-WT | Express His-tagged PKM2 (wild type) protein in bacteria. |
122691 | pET28a-PKM2-R399E | Express His-tagged PKM2 (R399E) protein in bacteria. |
122692 | pET28a-PKM2-H391Y | Express His-tagged PKM2 (H391Y) protein in bacteria. |
122693 | pET28a-PKM2-G415R | Express His-tagged PKM2 (G415R) protein in bacteria. |