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PTPN14 degradation by high-risk human papillomavirus E7 limits keratinocyte differentiation and contributes to HPV-mediated oncogenesis.

Hatterschide J, Bohidar AE, Grace M, Nulton TJ, Kim HW, Windle B, Morgan IM, Munger K, White EA
Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7033-7042. doi: 10.1073/pnas.1819534116. Epub 2019 Mar 20. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
163303p7612 MSCV-P C-FlagHA 16E7 E10KExpresses HPV16 E7 E10K
163304p7274 MSCV-P C-FlagHA 16 ∆DLYCExpresses HPV16 E7 ∆DLYC
163313p8103 LentiCRISPR v2 sgNT-2Expresses Cas9 and a non-targeting control guide RNA
163314p8115 LentiCRISPR v2 sgPTPN14-3Expresses Cas9 and a human PTPN14-targeting control guide RNA

Antibodies from Article