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Plasmid-Mediated Gene Therapy in Mouse Models of Limb Girdle Muscular Dystrophy.

Guha TK, Pichavant C, Calos MP
Mol Ther Methods Clin Dev. 2019 Oct 14;15:294-304. doi: 10.1016/j.omtm.2019.10.002. eCollection 2019 Dec 13. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
131456pgWIZ-SGCAglEncodes Alpha Sarcoglycan 3xFLAG tagged protein (Therapeutic gene) to cure LGMD2D and luciferase enzyme for in vivo live imaging
131457pKLD-CAG-DYSF-CFLEncodes Dysferlin protein (Therapeutic gene) along with Follistatin protein to cure LGMD2B along with luciferase enzyme for in vivo live imaging
131458pKLD-CAG-DYSF-CPLEncodes Dysferlin protein (Therapeutic gene) protein to cure LGMD2B along with luciferase enzyme for in vivo live imaging
131460p2attB-FST344-HA-CPLEncodes human Follistatin protein

Antibodies from Article