Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication.
Ardeljan D, Steranka JP, Liu C, Li Z, Taylor MS, Payer LM, Gorbounov M, Sarnecki JS, Deshpande V, Hruban RH, Boeke JD, Fenyo D, Wu PH, Smogorzewska A, Holland AJ, Burns KH
Nat Struct Mol Biol. 2020 Feb;27(2):168-178. doi: 10.1038/s41594-020-0372-1. Epub 2020 Feb 10.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 131380 | pDA007 | ORFeus expression, WT |
| 131384 | pDA025 | ORFeus expression, mutant |
| 131385 | pDA027 | ORFeus expression, mutant |
| 131386 | pDA034 | ORFeus expression, mutant |
| 131387 | pDA056 | ORFeus expression, WT |
| 131388 | pDA077 | L1RP expression |
| 131389 | pDA083 | eGFP expression |
| 131390 | pDA093 | generation of Tet-On RPE |
| 131391 | pDA095 | generation of Tet-On RPE |
| 131392 | pMT525 | L1RP retrotransposition reporter |
| 131452 | pDA019 | control expression vector |