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Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY.

Russelburg LP, O'Shea Murray VL, Demir M, Knutsen KR, Sehgal SL, Cao S, David SS, Horvath MP
ACS Chem Biol. 2019 Dec 27. doi: 10.1021/acschembio.9b00639. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
131376EcNGsC-MutY-pKK223Low level expression of E.coli G.stearothermophillus MutY chimera protein
131377EcNGsC-DelFSH(307-309)-pKK223Low level expression of E.coli G.stearothermophillus MutY chimera protein with deletion of residues FSH 307-309 in Gs MutY.
131378EcNGsC-S308P-H309D-pKK223Low level expression of E.coli G.stearothermophillus MutY chimera protein with amino acid changes S308P and H309D in Gs MutY.
131379EcNGsC-F307A-S308A-pKK223Low level expression of E.coli G.stearothermophillus MutY chimera protein with amino acid changes F307A and S308A in Gs MutY.
131381EcNGsC-F307Y-pKK223Low level expression of E.coli G.stearothermophillus MutY chimera protein with amino acid change F307Y in Gs MutY.
131382EcNGsC-F307A-pKK223Low level expression of E.coli G.stearothermophillus MutY chimera protein with amino acid change F307A in Gs MutY.
131393EcNGsC-S308V-pKK223Low level expression of E.coli G.stearothermophillus MutY chimera protein with amino acid change S308V in Gs MutY.
131394EcNGsC-S308A-pKK223Low level expression of E.coli G.stearothermophillus MutY chimera protein with amino acid change S308A in Gs MutY.

Antibodies from Article