Base editors for simultaneous introduction of C-to-T and A-to-G mutations.
Sakata RC, Ishiguro S, Mori H, Tanaka M, Tatsuno K, Ueda H, Yamamoto S, Seki M, Masuyama N, Nishida K, Nishimasu H, Arakawa K, Kondo A, Nureki O, Tomita M, Aburatani H, Yachie N
Nat Biotechnol. 2020 Jun 1. pii: 10.1038/s41587-020-0509-0. doi: 10.1038/s41587-020-0509-0.
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PubMed
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Article
Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
131124 | pRS0045 | Mammalian Target-ACE expression vector |
131125 | pRS0035 | Mammalian Target-AID expression vector |
131126 | pLV-SI-121 | A-to-G base editing reporter |
131127 | pLV-SI-112 | C-to-T base editing reporter |
131130 | pSI-535 | gRNA expression vector for C-to-T base editing reporter |
131131 | pSI-359 | gRNA expression vector for A-to-G base editing reporter |
139105 | pCMV-Target-ACEmax | Mammalian Target-ACEmax expression vector (pSI-625) |
139106 | pCMV-ACBEmax | Mammalian ACBEmax expression vector (pSI-632) |
139107 | pCMV-Target-AIDmax | Mammalian Target-AIDmax expression vector (pSI-626) |