PAC, an evolutionarily conserved membrane protein, is a proton-activated chloride channel.

Yang J, Chen J, Del Carmen Vitery M, Osei-Owusu J, Chu J, Yu H, Sun S, Qiu Z
Science. 2019 Apr 26;364(6438):395-399. doi: 10.1126/science.aav9739. Epub 2019 Apr 25. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID	Plasmid	Purpose
129488	pIRES2-hPAC	Expresses human TMEM206
129494	pIRES2-hPAC-FLAG	Expresses human TMEM206 tagged at the C-terminus with FLAG
129498	Zebrafish PAC (fPAC)	Expresses zebrafish TMEM206. In pcDNA3.1(+) backbone