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Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.

Matano M, Date S, Shimokawa M, Takano A, Fujii M, Ohta Y, Watanabe T, Kanai T, Sato T
Nat Med. 2015 Mar;21(3):256-62. doi: 10.1038/nm.3802. Epub 2015 Feb 23. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
129091pCR2.1-KRAS-G12VKI KRAS G12V mutation into human KRAS locus

Antibodies from Article