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Multiple Chemical Inducible Tal Effectors for Genome Editing and Transcription Activation.

Zhao C, Zhang Y, Zhao Y, Ying Y, Ai R, Zhang J, Wang Y
ACS Chem Biol. 2018 Mar 16;13(3):609-617. doi: 10.1021/acschembio.7b00606. Epub 2018 Jan 8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
1205442ERT2-AAVS1 TALEN-LDrug inducible TALEN targeting the human AAVS1 locus for genome editing
120546EF1a-3NLS-Klf4 TALE-GCN4Express 3xNLS-Klf4 TALE-GCN4 engineered to bind a site in the human KLF4 gene
120547EF1a-3NLS-NGN2TALE-GCN4Express 3xNLS-NGN2 TALE-GCN4 engineered to bind a site in the human NGN2 ene
120548EF1a-3NLS-Sox2TALE-GCN4Express 3xNLS-Sox2 TALE-GCN4 engineered to bind a site in the human SOX2 gene

Antibodies from Article