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Role of network-mediated stochasticity in mammalian drug resistance.

Farquhar KS, Charlebois DA, Szenk M, Cohen J, Nevozhay D, Balazsi G
Nat Commun. 2019 Jun 24;10(1):2766. doi: 10.1038/s41467-019-10330-w. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
128253pDN-D2irTN2AG5kwhMammalian linearizer gene circuit in a Flp-In expression system based on negative feedback. The hTetR and EGFP is separated by a P2A motif.
128254pKF-P14MM2AG5hMammalian positive feedback synthetic gene circuit within a Flp-In expression vector.
128255pKF-D2irTNP2AG-T2APuroR-5kwhMammalian linearizer gene circuit based on negative feedback in a Flp-In expression system controlling the PuroR gene.
128256pKF-P14MMP2AG-T2APuroR-5hMammalian positive feedback gene circuit in a Flp-In expression system controlling the PuroR gene. Also called mPF-PuroR.
128279pDN-D2irTNG5kwhMammalian linearizer gene circuit in a Flp-In expression system with a hTetR::EGFP fusion protein

Antibodies from Article