Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types.
Ravindra Kumar S, Miles TF, Chen X, Brown D, Dobreva T, Huang Q, Ding X, Luo Y, Einarsson PH, Greenbaum A, Jang MJ, Deverman BE, Gradinaru V
Nat Methods. 2020 May;17(5):541-550. doi: 10.1038/s41592-020-0799-7. Epub 2020 Apr 20.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 127847 | pUCmini-iCAP-PHP.V1 | non-standard AAV2 rep-AAV-PHP.V1 cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system |
| 127848 | pUCmini-iCAP-PHP.V2 | non-standard AAV2 rep-AAV-PHP.V2 cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system |
| 127849 | pUCmini-iCAP-PHP.B4 | non-standard AAV2 rep-AAV-PHP.B4 cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system |
| 127851 | pUCmini-iCAP-PHP.N | non-standard AAV2 rep-AAV-PHP.N cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system |