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NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation.

Lahaye X, Gentili M, Silvin A, Conrad C, Picard L, Jouve M, Zueva E, Maurin M, Nadalin F, Knott GJ, Zhao B, Du F, Rio M, Amiel J, Fox AH, Li P, Etienne L, Bond CS, Colleaux L, Manel N
Cell. 2018 Oct 4;175(2):488-501.e22. doi: 10.1016/j.cell.2018.08.062. Epub 2018 Sep 27. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
127650pLKO.1-puro-Nono-sh1Knock-down of human NONO
127651pLKO.1-puro-Nono-sh5Knock-down of human NONO
127652pLentiCRISPRv2-NONO 4Knock-out of human NONO
127653pLentiCRISPRv2-NONO 40Knock-out of human NONO
127654gRNA-NONO-1Knock-out of human NONO (guide only)
127655pcDNA3.1-HA-NONOOver-express HA-tagged human NONO

Antibodies from Article