Bloom syndrome protein restrains innate immune sensing of micronuclei by cGAS.
Gratia M, Rodero MP, Conrad C, Bou Samra E, Maurin M, Rice GI, Duffy D, Revy P, Petit F, Dale RC, Crow YJ, Amor-Gueret M, Manel N
J Exp Med. 2019 May 6;216(5):1199-1213. doi: 10.1084/jem.20181329. Epub 2019 Apr 1.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 127641 | pTRIP-CMV-puro-2A-BLM | Over-expression of human BLM |
| 127642 | pLentiCRISPRv2 sgIRF3#5 | Knock-out of human IRF3 |
| 127643 | pLentiCRISPRv2 sgBLM10 | Knock-out of human BLM |
| 127644 | pLentiCRISPRv2 Neo | Empty pLentiCRISPRv2 with NeoR |
| 127645 | pLentiCRISPRv2 Neo sgTREX1 | Knock-out of human TREX1 with NeoR |
| 127646 | pLKO.1-puro-cGASsh4 | Knock-down of human cGAS |
| 127647 | pLKO.1-puro-STING-sh5 | Knock-down of human STING |
| 127648 | pLKO.1-puro-irf3-shrna1 | Knock-down of human IRF3 |
| 127649 | pLKO.1-puro-irf3-shrna5 | Knock-down of human IRF3 |