Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells.
Tan J, Sharief Y, Hamil KG, Gregory CW, Zang DY, Sar M, Gumerlock PH, deVere White RW, Pretlow TG, Harris SE, Wilson EM, Mohler JL, French FS
Mol Endocrinol. 1997 Apr;11(4):450-9. doi: 10.1210/mend.11.4.9906.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
89087 | pCMV-hAR-H874Y | mammalian expression of human androgen receptor with prostate cancer somatic mutation H874Y from CWR22 xenograft |