A new small molecule inhibitor of estrogen receptor alpha binding to estrogen response elements blocks estrogen-dependent growth of cancer cells.
Mao C, Patterson NM, Cherian MT, Aninye IO, Zhang C, Montoya JB, Cheng J, Putt KS, Hergenrother PJ, Wilson EM, Nardulli AM, Nordeen SK, Shapiro DJ
J Biol Chem. 2008 May 9;283(19):12819-30. doi: 10.1074/jbc.M709936200. Epub 2008 Mar 12.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
101141 | pCMV-hERalpha | Mammalian expression of full-length human estrogen receptor-alpha |