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A new small molecule inhibitor of estrogen receptor alpha binding to estrogen response elements blocks estrogen-dependent growth of cancer cells.

Mao C, Patterson NM, Cherian MT, Aninye IO, Zhang C, Montoya JB, Cheng J, Putt KS, Hergenrother PJ, Wilson EM, Nardulli AM, Nordeen SK, Shapiro DJ
J Biol Chem. 2008 May 9;283(19):12819-30. doi: 10.1074/jbc.M709936200. Epub 2008 Mar 12. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
101141pCMV-hERalphaMammalian expression of full-length human estrogen receptor-alpha

Antibodies from Article