A rationally designed pyrrolysyl-tRNA synthetase mutant with a broad substrate spectrum.
Wang YS, Fang X, Wallace AL, Wu B, Liu WR
J Am Chem Soc. 2012 Feb 15;134(6):2950-3. doi: 10.1021/ja211972x. Epub 2012 Feb 6.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 127411 | pEVOL-pylT-N346A/C348A | Double mutant of wild type mmPylRS designed for incorporation of non-canonical amino acids with mono-substituted phenylalanine derivatives and tyrosinyl ethers |