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Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans.

Juttner J, Szabo A, Gross-Scherf B, Morikawa RK, Rompani SB, Hantz P, Szikra T, Esposti F, Cowan CS, Bharioke A, Patino-Alvarez CP, Keles O, Kusnyerik A, Azoulay T, Hartl D, Krebs AR, Schubeler D, Hajdu RI, Lukats A, Nemeth J, Nagy ZZ, Wu KC, Wu RH, Xiang L, Fang XL, Jin ZB, Goldblum D, Hasler PW, Scholl HPN, Krol J, Roska B
Nat Neurosci. 2019 Jul 8. pii: 10.1038/s41593-019-0431-2. doi: 10.1038/s41593-019-0431-2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
125886136_pAAV-ProA1-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125887137_pAAV-ProA3-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125888155_pAAV-ProA4-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12588988_pAAV-ProA5-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125890I_pAAV-ProA6-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125891VI_pAAV-ProA7-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
1258923_pAAV-ProA8-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
1258935_pAAV-ProA9-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12589428_pAAV-ProA10-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12589553_pAAV-ProA11-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12589655_pAAV-ProA13-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12589757_pAAV-ProA14-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12589858_pAAV-ProA15-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12589959_pAAV-ProA16-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12590060_pAAV-ProA17-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12590161_pAAV-ProA18-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12590262_pAAV-ProA19-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12590364_pAAV-ProA20-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12590466_pAAV-ProA21-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12590568_pAAV-ProA22-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12590670_pAAV-ProA23-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12590771_pAAV-ProA24-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12590876_pAAV-ProA25-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12590977_pAAV-ProA26-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12591078_pAAV-ProA27-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12591195_pAAV-ProA28-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12591298_pAAV-ProA29-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125913100_pAAV-ProA30-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125914102_pAAV-ProA31-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125915127_pAAV-ProA32-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125916140_pAAV-ProA33-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125917146_pAAV-ProA34-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125918193_pAAV-ProA35-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
1259206_pAAV-ProA37-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12592117_pAAV-ProB1-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125922132_pAAV-ProB2-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125923IX_pAAV-ProB3-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125924III_pAAV-ProB4-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125925II_pAAV-ProB5-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125926IV_pAAV-ProB6-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125928VII_pAAV-ProB8-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125929VIII_pAAV-ProB9-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
1259307_pAAV-ProB10-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12593126_pAAV-ProB11-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12593227_pAAV-ProB12-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125933131_pAAV-ProB13-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125934169_pAAV-ProB14-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125935194_pAAV-ProB15-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125937123_pAAV-ProC1-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12593812_pAAV-ProC2-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125939124_pAAV-ProC3-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
1259408_pAAV-ProC4-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
1259419_pAAV-ProC5-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12594211_pAAV-ProC6-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12594335_pAAV-ProC8-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12594440_pAAV-ProC9-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12594545_pAAV-ProC10-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12594646_pAAV-ProC11-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12594751_pAAV-ProC12-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12594882_pAAV-ProC13-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12594983_pAAV-ProC14-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125950104_pAAV-ProC15-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125951105_pAAV-ProC16-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125952107_pAAV-ProC17-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125953108_pAAV-ProC18-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125954109_pAAV-ProC19-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125955110_pAAV-ProC20-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125956113_pAAV-ProC21-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125957114_pAAV-ProC22-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125958115_pAAV-ProC23-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125959116_pAAV-ProC24-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125960119_pAAV-ProC25-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125961120_pAAV-ProC26-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125962121_pAAV-ProC27-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125964151_pAAV-ProC29-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125965152_pAAV-ProC30-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125966153_pAAV-ProC31-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125968167_pAAV-ProC34-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125969168_pAAV-ProC35-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125970171_pAAV-ProC36-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125971172_pAAV-ProC37-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125972173_pAAV-ProC38-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125973174_pAAV-ProC39-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12597437_pAAV-ProC40-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12597542_pAAV-ProC41-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
12597613_pAAV-ProC71-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125977198_pAAV-ProD1-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125978157_pAAV-ProD2-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125979159_pAAV-ProD3-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125980160_pAAV-ProD4-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125981161_pAAV-ProD5-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125984177_pAAV-ProD8-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125985178_pAAV-ProD9-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125986179_pAAV-ProD10-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125987180_pAAV-ProD11-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125988181_pAAV-ProD12-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125989182_pAAV-ProD13-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125990183_pAAV-ProD14-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125991184_pAAV-ProD15-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125992185_pAAV-ProD16-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125993206_pAAV-ProD17-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125994209_pAAV-ProD18-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125995210_pAAV-ProD19-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125996211_pAAV-ProD20-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125997212_pAAV-ProD21-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125998214_pAAV-ProD22-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
125999215_pAAV-ProD23-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
126000216_pAAV-ProD24-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
126001217_pAAV-ProD25-CatCh-GFP-WPRETargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
126002pAAV-ProA1-GCaMP6sTargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
126003pAAV-ProA5-GCaMP6sTargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
126004pAAV-ProA18-GCaMP6sTargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
126005pAAV-ProD1-GCaMP6sTargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina
126006pAAV2-ProC3-Cre/mCherryTargeting expression to neuronal and glial cell types in mice, non-human primates, and human retina

Antibodies from Article