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BAP1 links metabolic regulation of ferroptosis to tumour suppression.

Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, Sirohi K, Li X, Wei Y, Lee H, Zhuang L, Chen G, Xiao ZD, Hung MC, Chen J, Huang P, Li W, Gan B
Nat Cell Biol. 2018 Oct;20(10):1181-1192. doi: 10.1038/s41556-018-0178-0. Epub 2018 Sep 10. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
125836lentiCRISPR v2-sgControlKO control
125837lentiCRISPR v2-sgBAP1-1KO BAP1 gene
125838lentiCRISPR v2-sgBAP1-2KO BAP1 gene
125839pLVX-M-puromodifying MCS, replacing EcoRI to BamHI region with BamHI and EcoRI
125840pLVX-M-Flag-BAP1express wild type BAP1
125841pLVX-M-Flag-BAP1-C91Aexpress mutant BAP1-C91A
125842pLVX-M-Flag-BAP1-S10Texpress mutant BAP1-S10T
125843pLVX-M-Flag-BAP1-E31Aexpress mutant BAP1-E31A
125844pLVX-M-Flag-BAP1-L49Vexpress mutant BAP1-L49V
125845pLVX-M-Flag-BAP1-C91Gexpress mutant BAP1-C91G
125846pLVX-M-Flag-BAP1-G109Vexpress mutant BAP1-G109V
125847pLVX-M-Flag-BAP1-H169Qexpress mutant BAP1-H169Q
125848pLVX-M-Flag-BAP1-F170Cexpress mutant BAP1-F170C
125849pLVX-M-Flag-BAP1-G185Rexpress mutant BAP1-G185R

Antibodies from Article